Hereditary Cancer Test Offerings

Test Name

Test Code

Comprehensive Hereditary Cancer Panel (66 genes)

APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, DICER1, EGFR, EPCAM, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, GREM1, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN,RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2

907263

Guideline-Based Hereditary Cancer Panel (32 genes)

APC, ATM, AXIN2, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A (p16,p14), CHEK2, EPCAM, GREM1, HOXB13, MLH1, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53

Hereditary Colorectal Cancer Panel (19 genes)

APC, AXIN2, BMPR1A, CDH1, EPCAM, GREM1, MLH1, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, SMAD4, STK11, TP53

BRCA Panel (BRCA1, BRCA2) 

BRCA1, BRCA2

BRCA Ashkenazi Jewish Screen

Common founder variants BRCA1 c.68_69delAG, BRCA1 c.5266dupC, BRCA2 c.5946delT

BRCA Ashkenazi Jewish Screen w/ Reflex to BRCA Panel (BRCA1, BRCA2)

Ashkenazi Jewish screen; if negative reflex to BRCA Panel-BRCA1 and BRCA2

BRCA1 and BRCA2 Deletion and Duplication

Detects large deletions/duplications in the BRCA1 and BRCA2 genes which are not detectable by DNA sequencing

Lynch Syndrome Panel (5 genes)

MLH1, MSH2, MSH6, PMS2, and EPCAM (deletion/duplication only)